Studii clinice

Boli inflamatorii intestinale

Referințe și publicații relevante despre rolul studiat al HBOT în bolile inflamatorii intestinale.

HBOT ca opțiune adjuvantă pentru reducerea inflamației și susținerea vindecării mucoasei

Deși studii de amploare privind utilizarea oxigenoterapiei hiperbare în bolile inflamatorii intestinale sunt încă în stadiu incipient, rezultatele inițiale sunt promițătoare, arătând că terapia hiperbară poate ajuta la reducerea durerii, inflamației și a simptomelor, oferind o opțiune de tratament promițătoare pentru pacienții cu boli inflamatorii intestinale.

În timp ce tratamentele clasice bazate pe corticosteroizi, antiinflamatoare și imunomodulatoare pot produce efecte secundare grave pe termen lung, terapia hiperbară poate reprezenta o nouă opțiune de tratament, deoarece vizează atât hipoxia tisulară, cât și inflamația, cu foarte puține efecte secundare.

Bibliografie

Publicații și referințe

Yong Li, Ruizheng Sun, Chen Lai, Kezhen Liu, Huixiang Yang, Ziheng Peng, Duo Xu, Fangling Huang, Keke Tang, Yu Peng, Xiaowei Liu

Hyperbaric oxygen therapy ameliorates intestinal and systematic inflammation by modulating dysbiosis of the gut microbiota in Crohn's disease

J Transl Med. 2024 May 30;22(1):518. doi: 10.1186/s12967-024-05317-1

Marley R. Feitosa, Rogério S. Parra, Vanessa F. Machado, Gustavo N. Vilar, Jussara C. Aquino, José J. R. Rocha, Paulo G. Kotze, Omar Féres

Adjunctive Hyperbaric Oxygen Therapy in Refractory Crohn’s Disease: An Observational Study

First published: 27 April 2021; https://doi.org/10.1155/2021/6628142

Anupam Kumar Singh, Daya Krishna Jha, Anuraag Jena, Praveen Kumar-M, Shaji Sebastian and Vishal Sharma

Hyperbaric oxygen therapy in inflammatory bowel disease: a systematic review and meta-analysis

April 2021 European Journal of Gastroenterology & Hepatology, Publish Ahead of Print(1S Suppl 1); DOI: 10.1097/MEG.0000000000002164

Mohamed Bekheit, Nahed Baddour, Khaled Katri, Yousry Taher, Khaled El Tobgy, Essam Mousa

Hyperbaric oxygen therapy stimulates colonic stem cells and induces mucosal healing in patients with refractory ulcerative colitis: a prospective case series

BMJ Open Gastroenterology 2016;3:e000082. doi: 10.1136/bmjgast-2016-000082

Corine A. Lansdorp, Christianne J. Buskens, Krisztina B. Gecse, Mark Löwenberg, Jaap Stoker, Willem A. Bemelman, Geert R. A. M. D’Haens, Rob A. van Hulst

Hyperbaric oxygen therapy for the treatment of perianal fistulas in 20 patients with Crohn's disease: Results of the HOT-TOPIC trial after 1-year follow-up

First published: 10 February 2022; https://doi.org/10.1002/ueg2.12189

P. S. Dulai, M. W. Gleeson, D. Taylor, S. D. Holubar, J. C. Buckey, C. A. Siegel

Systematic review: the safety and efficacy of hyperbaric oxygen therapy for inflammatory bowel disease

First published: 16 April 2014; https://doi.org/10.1111/apt.12753

Jiu-hong You, Jun-liang Jiang, Wen-bo He, Hui Ma, Mei Zhou, Xin-xin Chen, Qiao-ling Liu, and Cheng Huanga

Addition of hyperbaric oxygen therapy versus usual care alone for inflammatory bowel disease: A systematic review and meta-analysis

Heliyon. 2022 Oct; 8(10): e11007; Published online 2022 Oct 13; DOI: 10.1016/j.heliyon.2022.e11007; PMCID: PMC9583108; PMID: 36276722

Carlos G. Gonzalez, Robert H. Mills, Melissa C. Kordah, Marvic Carrillo-Terrazas, Henry Secaira-Morocho, Christella E. Widjaja, Matthew S. Tsai, Yash Mittal, Brian A. Yee, Fernando Vargas, Kelly Weldon, Julia M. Gauglitz, Clara Delaroque, Consuelo Sauceda, Leigh-Ana Rossitto, Gail Ackermann, Gregory Humphrey, Austin D. Swafford, Corey A. Siegel, Jay C. Buckey Jr., Parambir S. Dulai

The Host-Microbiome Response to Hyperbaric Oxygen Therapy in Ulcerative Colitis Patients

https://doi.org/10.1016/j.jcmgh.2022.03.008

Corine A Lansdorp, Christianne J Buskens, Krisztina B Gecse, Geert RAM D’Haens and Rob A Van Hulst

Wound healing of metastatic perineal Crohn’s disease using hyperbaric oxygen therapy: A case series

https://doi.org/10.1177/2050640620934915

Badar Hasan MD, Yunjoo Yim MD, Mamoon Ur Rashid MD, Rumman A Khalid MD, Deepika Sarvepalli MD, Daniel Castaneda MD, Asad Ur Rahman MD, Nicole Palekar MD, Roger Charles MD, Fernando J Castro MD, Bo Shen MD

Hyperbaric Oxygen Therapy in Chronic Inflammatory Conditions of the Pouch

Inflammatory Bowel Diseases, Volume 27, Issue 7, July 2021, Pages 965–970; https://doi.org/10.1093/ibd/izaa245

Naif Alenazi, Hesham Alsaeed, Adel Alsulami, and Turki Alanzi

A Review of Hyperbaric Oxygen Therapy for Inflammatory Bowel Disease

Int J Gen Med. 2021; 14: 7099–7105; Published online 2021 Oct 24. DOI: 10.2147/IJGM.S336678; PMCID: PMC8554584; PMID: 34729019

Bhaskar Kante, Pabitra Sahu, Saurabh Kedia, Sudheer K. Vuyyuru, Kapil Soni, Maneesh Singhal, Raju Sharma, Govind Makharia, Vineet Ahuja

Efficacy and tolerability of hyperbaric oxygen therapy in small bowel stricturing Crohn’s disease: a pilot study

Intestinal Research 2022;20(2):231-239

A Hillary Steinhart, Remo Panaccione, Laura Targownik, Brian Bressler, Reena Khanna, John K Marshall, Waqqas Afif, Charles N Bernstein, Alain Bitton, Mark Borgaonkar, Usha Chauhan, Brendan Halloran, Jennifer Jones, Erin Kennedy, Grigorios I Leontiadis, Edward V Loftus Jr, Jonathan Meddings, Paul Moayyedi, Sanjay Murthy, Sophie Plamondon, Greg Rosenfeld, David Schwartz, Cynthia H Seow, and Chadwick Williams

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Boli inflamatorii intestinale

HBOT ca opțiune adjuvantă pentru reducerea inflamației și susținerea vindecării mucoasei

Publicații și referințe

Hyperbaric oxygen therapy ameliorates intestinal and systematic inflammation by modulating dysbiosis of the gut microbiota in Crohn's disease

Adjunctive Hyperbaric Oxygen Therapy in Refractory Crohn’s Disease: An Observational Study

Hyperbaric oxygen therapy in inflammatory bowel disease: a systematic review and meta-analysis

Hyperbaric oxygen therapy stimulates colonic stem cells and induces mucosal healing in patients with refractory ulcerative colitis: a prospective case series

Hyperbaric oxygen therapy for the treatment of perianal fistulas in 20 patients with Crohn's disease: Results of the HOT-TOPIC trial after 1-year follow-up

Systematic review: the safety and efficacy of hyperbaric oxygen therapy for inflammatory bowel disease

Addition of hyperbaric oxygen therapy versus usual care alone for inflammatory bowel disease: A systematic review and meta-analysis

The Host-Microbiome Response to Hyperbaric Oxygen Therapy in Ulcerative Colitis Patients

Wound healing of metastatic perineal Crohn’s disease using hyperbaric oxygen therapy: A case series

Hyperbaric Oxygen Therapy in Chronic Inflammatory Conditions of the Pouch

A Review of Hyperbaric Oxygen Therapy for Inflammatory Bowel Disease

Efficacy and tolerability of hyperbaric oxygen therapy in small bowel stricturing Crohn’s disease: a pilot study

Clinical Practice Guideline for the Medical Management of Perianal Fistulizing Crohn’s Disease: The Toronto Consensus

Hyperbaric oxygen treatment for inflammatory bowel disease: a systematic review and analysis

Systematic review with meta-analysis: effectiveness of hyperbaric oxygenation therapy for ulcerative colitis

Hyperbaric Oxygen Therapy in the Treatment of Crohn’s Disease

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