Studii clinice

Arsuri, opăriri, degerături

Selecție editorială de publicații și lucrări relevante despre utilizarea terapiei hiperbare în contextul arsurilor, opăririlor și degerăturilor.

Rolul studiat al HBOT în leziunile acute ale țesuturilor

Literatura medicală citată în această pagină urmărește modul în care terapia cu oxigen hiperbaric este analizată ca suport în managementul arsurilor termice, chimice sau prin iradiere, al opăririlor și al degerăturilor. În aceste contexte, oxigenarea suplimentară este investigată pentru efectele sale asupra perfuziei locale, răspunsului inflamator și proceselor de reparare tisulară.

Mai multe lucrări discută potențialul terapiei de a susține vindecarea prin îmbunătățirea aportului de oxigen în zonele afectate, prin stimularea angiogenezei și prin integrarea într-un plan terapeutic mai amplu, adaptat severității leziunii și indicației medicale.

Selecția de mai jos reunește articole, serii de cazuri, revizuiri și publicații recente folosite ca punct de pornire pentru documentare profesională și pentru orientarea clinică responsabilă.

Bibliografie

Publicații și referințe

Nabila Fairuz Sari, Ahmad Fawzy

A Deep Dive into the Role of Hyperbaric Oxygen Therapy in Enhancing Burn Wound Healing

DOI: https://doi.org/10.47191/ijmscrs/v4-i05-30, Impact Factor: 7.949

Omer A. Idris, Alexandra L. Uridge, Syann Hollins, Kyle Ver Steeg II

Evaluating the Role of Hyperbaric Oxygen Therapy in Enhancing Skin Graft Outcomes: Mechanisms, Clinical Evidence, and Comparative Efficacy

Oxygen 2024, 4(4), 377-388; https://doi.org/10.3390/oxygen4040023

Joerg Lindenmann, Christian Smolle, Lars-Peter Kamolz, Freyja Maria Smolle-Juettner, Wolfgang F Graier

Survey of Molecular Mechanisms of Hyperbaric Oxygen in Tissue Repair

PMCID: PMC8584249 PMID: 34769182

E Pathault, S Sanchez, B Husson, C Vanhaecke, P Georges, C Brazier, B Mourvillier, M Viguier

Hyperbaric oxygen therapy enables pain reduction and healing in painful chronic wounds, including in calciphylaxis

PMID: 39579606 DOI: 10.1016/j.annder.2024.103325

Jaskomal Phagoora, Brett Agrest, Moshe Kabariti, Sukhpreet Saini, Yanni Hedjar

A Rare Bacteremia in a Patient With Osteomyelitis and Sacral Ulcer: A Case Report of Tissierella praeacuta and Parvimonas micra

Published: November 23, 2024; DOI: 10.7759/cureus.74314

Aldrin L. Myrthong, Shrutika Gurav, Suresh Mahankudo, Kashif F. Ansari, Manasi Sawant, Kaushal Lahoti

Hyperbaric Oxygen Therapy Combined With Standard Wound Care Versus Standard Wound Care Alone in Patients With Diabetic Foot Ulcers: A Prospective Comparative Study

Published: December 02, 2024; DOI: 10.7759/cureus.74964

Ammara Ghumman, Hannah St Denis-Katz, Rosalind Ashton, Christopher Wherrett, Claudia Malic

Treatment of Frostbite With Hyperbaric Oxygen Therapy: A Single Center's Experience of 22 Cases

PMID: 31730511

Ghosh DD, Udaya IB, Pipraiya R, Ghosh PC

HBOT in Frostbite: Less Explored Modality with Excellent Outcome

Case Report 60(2);42-48, Published: 2016-12-31

Hind Taoufik, Adil Arrob, Ouafa Hocar, Taoufik Nassim Sabah, Amal Said and Khalid Tourabi

Contribution of Hyperbaric Oxygen Therapy to the Healing of Infected Burn Wound

10.21474/IJAR01/14383

I-Han Chiang; Shyi-Gen Chena Kun-Lun Huang; Yu-Ching Chou; Niann-Tzyy Dai; Chung-Kan Peng

Adjunctive hyperbaric oxygen therapy in severe burns: Experience in Taiwan Formosa Water Park dust explosion disaster

Accepted 12 October 2016, Available online 27 December 2016, Version of Record 4 May 2017

V. M. Rasmussen, A. E. Borgen, E. C. Jansen, P. H. Rotbøll Nielsen, M. U. Werner

Hyperbaric oxygen therapy attenuates central sensitization induced by a thermal injury in humans

Acta Anaesthesiologica Scandinavica Volume 59, Issue 6 p. 749-762

Oley Mendy Hatibie, Oley Maximillian Christian, Noersasongko Albertus Djarot, Islam Andi Asadul, Tulong Marcella Tirsa; Siwabessy Melfritsh; Panduwinata Dicky, Faruk Muhammad

Hyperbaric oxygen therapy in low extremity trauma: A case series

Annals of Medicine & Surgery 78():p 103896, June 2022. | DOI: 10.1016/j.amsu.2022.103896

Mendy Hatibie Oley, Maximillian Christian Oley, Deanette Michelle R. Aling, Jane Angela Kalangi, Andi Asadul Islam, Mochammad Hatta, Ilham Jaya Patellongi, Fonny Joshi Muhammad Faruk

Effects of hyperbaric oxygen therapy on the healing of thermal burns and its relationship with ICAM-1: A case-control study

Annals of Medicine and Surgery Volume 61, January 2021, Pages 104-109

Brian Higdon, Laura Youngman, Michelle Regehr, Andy Chiou

Deep Frostbite Treated With Hyperbaric Oxygen and Thrombolytic Therapies

Index Wounds 2015;27(8):215-223

Hakan Ay, Senol Yildiz, Gunalp Uzun, Emrullah Solmazgul, Kadir Dundar, Ismail Yildirim

The treatment of deep frostbite with hyperbaricoxygen

Injury Extra (2005) 36. 499-502

Chin-An Chen, Yi-Chen Huang, Jing-Jou Lo, Shih-Hung Wang, Shu-Hung Huang, and Sheng-Hua Wu

Hyperbaric Oxygen Therapy Attenuates Burn-Induced Denervated Muscle Atrophy

Int J Med Sci. 2021; 18(16): 3821–3830; Published online 2021 Oct 25. DOI: 10.7150/ijms.65976; PMCID: PMC8579280; PMID: 34790058

M. Mohamed Arafath, R. Viswanathan

Hyperbaric Oxygen for Thermal Burn and Electrical Burn Wound Healing – A Case Report

International Journal of Scientific Study | March 2021 | Vol 8 | Issue 12

Marie-Anne Magnan, Angèle Gayet-Ageron, Pierre Louge, Frederic Champly, Thierry Joffre, Christian Lovis and Rodrigue Pignel

Hyperbaric Oxygen Therapy with Iloprost Improves Digit Salvage in Severe Frostbite Compared to Iloprost Alone

Medicina 2021, 57(11), 1284; https://doi.org/10.3390/medicina57111284

Les Roger Folio, USAF MC SFS, Keren Arkin, ENS, William P. Butler, MD, MTMH, FACS

Frostbite in a Mountain Climber Treated with Hyperbaric Oxygen: Case Report

Military Medicine, Volume 172, Issue 5, May 2007, Pages 560–563, https://doi.org/10.7205/MILMED.172.5.560 Published: 01 May 2007

Corine A Lansdorp, Gert R Roukema, Onno Boonstra, Jan Dokter, Cees van der Vlies

Delayed treatment of frostbite with hyperbaric oxygen: a report of two cases

PMID: 28783893 DOI: 10.22462/7.8.2017.9

Anna M Wahl, Daniel Bidstrup, Isabel G Smidt-Nielsen, Mads U Werner, Ole Hyldegaard, Per Rotbøll-Nielsen

A single session of hyperbaric oxygen therapy demonstrates acute and long-lasting neuroplasticity effects in humans: a replicated, randomized controlled clinical trial

Published 31 July 2019 Volume 2019:12 Pages 2337—2348

Tawfeik Alyafi; Al-Hasan H. Al-Marzouki Abdulaziz N. Al Hassani

Therapeutic Outcome of Burn Patients Treated With Hyperbaric Oxygen

Published: October 11, 2021; DOI: 10.7759/cureus.18671

Laura Marín, Graciela Fioravanti, Elisabet Cristaldo, Carlos Emilio Sereday, Oscar Merbilhaá, Mercedes Portas

Hyperbaric oxygen therapy for a pediatric electrical burn: A case report

Received 18 March 2020, Revised 23 April 2020, Accepted 3 May 2020, Available online 15 May 2020, Version of Record 13 July 2020

Igor B. Mekjavic, Jurij Gorjanc, Polona Jaki Mekjavic, Fajko Bajrovic, Metka Milcinski

Hyperbaric Oxygen as an Adjunct Treatment of Freezing Cold Injury

RTO-MP-HFM-126

Wafaa Borhan, Maher El Kebelawy, and Ashraf EI Sebaie

Efficacy of Hyperbaric Oxygen Therapy on Second Degree of Burn Wound of Forearm

The Egyptian Journal of Hospital Medicine Vol., 22 : 183- 189; March 2006; I.S.S.N: 12084; 2002-1687

Anil Pinninti, Vivek Verma, S Narayan, Amitabh Mohan

Hyperbaric oxygen therapy in frostbite: A case serie

Year : 2022 | Volume : 24 | Issue : 3 | Page : 110-113; DOI: 10.4103/jmms.jmms_23_21

Esmee Kwee, Marieke Borgdorff, Tim Schepers, Jens A. Halm, Hay A. H. Winters, Robert P. Weenink, Milan L. Ridderikhof & Georgios F. Giannakópoulos

Adjunctive hyperbaric oxygen therapy in the management of severe lower limb soft tissue injuries: a systematic review

Published: 22 February 2024

Caterina Marra, Paola Pentangelo, Luigi Losco, Alessandra Ceccaroni, Alfonso Barbato and Carmine Alfano

Lower Extremity Trauma: A Multidimensional Reconstructive Approach with Hyperbaric Oxygen Therapy

J. Clin. Med. 2024, 13(5), 1407; https://doi.org/10.3390/jcm13051407

Shivangi S, Amiteshwar S, Shruthi C, Soumya G, Maneesh S and Sushma S

Hyperbaric Oxygen Therapy: A Must for Trauma Centers?

Journal of Plastic Surgery, Published: 14 Aug, 2023

Levent Demir, Mustafa Öztürk

Use of hyperbaric oxygen therapy in severe earthquake injuries

PMID: 38506387 DOI: 10.14744/tjtes.2024.60979

Pradeoth Mukundan Korambayil, Hemang Arvind Sanghvi, Vinoth Kumar Dilliraj, Prashanth Varkey Ambookan

Evaluating Hyperbaric Oxygen Therapy to Improve Single-Stage Dermal Substitute and Skin Grafting: A Comparative Study

PMID: 39741730 PMCID: PMC11684969 DOI: 10.1055/s-0044-1788592

Chao Xue, Hao Chen, Yiou Zhao, Dai Yuan, Xiaosheng Fang, Mei Ding, Huiting Qu, Xin Wang, Xueling Ge, Kang Lu, Yujie Jiang

Preventive Hyperbaric Oxygen Therapy Improves Acute Graft-Versus-Host Disease by Activating the Nrf2/HO-1 Pathway Provisionally accepted

Front. Immunol., Sec. Alloimmunity and Transplantation, Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1529176

Marin Marinović, Tanja Batinac, Goran Slivšek, Ivica Jendrašic, Endi Radović, Vedrana Muzic, Ante Bandalović, Klara Radović, Dean Markic, Davor Primc, Enesa Kadirić, Melita Kukuljan

The Combination of Extracellular Matrix (ECM) and Hyperbaric Oxygen Therapy (HBOT) in the Treatment of Mutilated Foot Injury: A Winning Combination?

March 2025, DOI:10.13140/RG.2.2.15557.15845

Mendy Hatibie Oley, Maximillian Christian Oley, Albertus Djarot Noersasongko, Yudhaputra Setiadhi, Vania Sukarno, Muhammad Faruk

Hyperbaric oxygen therapy in managing fingertip injury after the thenar and Vsingle bondY flap procedure: A case series

https://doi.org/10.1016/j.ijscr.2025.111265

Thanaporn Riansrithongkham, Pangrum Yongchareon, Ajana Sivadechathep, Anucha Likitvong, Terasak Mahamongkol, Chatchai Pruksapong

Efficacy of Hyperbaric Oxygen Therapy Combine with Negative Pressure Wound Therapy in Chronic Wound: A randomized controlled trial

https://doi.org/10.1016/j.jpra.2025.05.001

Thomas J. Gregory, Kinjal Sethuraman

The Role of Hyperbaric Oxygen Therapy in Management of Necrotizing Soft Tissue Infection

J. Clin. Med. 2025, 14(10), 3511; https://doi.org/10.3390/jcm14103511; Submission received: 16 April 2025 / Revised: 9 May 2025 / Accepted: 13 May 2025 / Published: 17 May 2025

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